On-Dyskinesia refers to the choreic and dystonic movements described as “jerking or twisting movements that occur when your medicine is working.”

• Jerking or twisting movements that occur when patient's medicine is working to control Parkinsonism.
• It does not concern with tremor, which is a regular back and forth shaking.
• Neither does it concern with any part of the slowness or stiffness of Parkinson’s disease itself,
• Nor with spasms that occur when patient's medications are not working or when patients do not take their medication for Parkinson’s disease.
• It has only something to do with the jerking or twisting movements that occur when the patient's medicine is working to control his/her Parkinson’s disease.

Off-Dystonia is described as “spasms or cramps that can be painful and occur when your Parkinson’s disease medications are not taken or are not working.

• Spasms or cramps that occur when the Parkinson’s disease medications are not taken or are not working well.
• That time period is called OFF.
• Off-dystonia is sometimes painful and often occurs in the early morning or nighttime, but occasionally at other times as well when Parkinson’s disease medications are not working.
• The feet and toes can be affected or other body areas.
• It does not concern with tremor, which is a regular back and forth shaking.
• Neither does it concern about the slowness or stiffness of Parkinson’s disease itself,
• Nor with the jerking or twisting movements called dyskinesia.
• Only concerns with spasms or cramps that are called OFF-Dystonia